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Researchers discovered that declining levels of phosphatidylcholine may be a major cause of age-related mitochondrial dysfunction and loss of cellular energy. Remarkably, boosting this nutrient restored more youthful mitochondrial performance in aging organisms, suggesting some aspects of aging can be slowed or reversed.
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A groundbreaking new connectome maps every neural connection in an adult fruit fly’s central nervous system, creating an unprecedented view of how the brain and body work together. The findings suggest that complex behaviors emerge from distributed local circuits rather than a single central controller, offering new clues about intelligence, movement, and brain function.
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Researchers gave top AI models a classic attention test used in psychology and found a major flaw. While the models could correctly name colors in short lists, their performance deteriorated sharply as the task became longer and more complex. Some leading systems fell from over 90% accuracy to nearly complete failure.
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MIT researchers have shown that one fuel can power both chemical and electric spacecraft thrusters, potentially transforming what small satellites can do. The approach combines quick bursts of speed with highly efficient long-range propulsion in a single compact system. A NASA-supported CubeSat mission will soon test the technology in orbit.
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A surprising gut-heart connection may help explain why sleep apnea increases the risk of cardiovascular disease. In mice, disabling a bile acid receptor called FXR sharply reduced plaque buildup, opening the door to potential new treatments based on gut microbes and their chemical signals.
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Scientists have uncovered new evidence that Stonehenge’s six-ton Altar Stone was deliberately transported hundreds of kilometers from Scotland by ancient people. The feat would have required extraordinary planning, teamwork, and determination, revealing a surprisingly sophisticated level of organization thousands of years ago.
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The mysterious Amaterasu particle may not be a proton at all. New research suggests that some of the most extreme cosmic rays could be ultraheavy atomic nuclei, heavier than iron, which are better able to retain their energy while traveling through space. This idea could help explain how these rare particles reach Earth and provide new clues about the powerful cosmic explosions that create them.
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A study of more than 2,100 adults found that eating more ultra-processed foods was linked to poorer attention and slower mental processing, even among people with otherwise healthy diets. Researchers also found higher consumption was associated with increased dementia risk factors, raising concerns about the hidden cognitive costs of heavily processed foods.
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“Chemo brain” affects up to 80% of people receiving chemotherapy, making everyday tasks harder. In a new trial, cancer patients who followed a home-based exercise program showed better attention and fewer noticeable cognitive problems than those who received a placebo. Low-dose ibuprofen also improved some cognitive measures, though its effects were less consistent.
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Scientists have uncovered a hidden immune system "brake" that may help cancers avoid being destroyed. The molecule, called SLAMF6, weakens the body's cancer-fighting T cells and can leave them exhausted over time. Researchers developed antibodies that block this brake, allowing immune cells to stay stronger and attack tumors more effectively in mice.
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The largest review ever conducted on opioids for acute pain found that these widely prescribed drugs often deliver only small, short-lived benefits. For many common conditions, including some surgeries and kidney stone pain, opioids performed no better than a placebo. Researchers also found higher rates of side effects and warned that dependence can begin after only a short period of use.
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A surprising study suggests that chemicals introduced to protect the ozone layer may have unintentionally created a growing global pollution problem. Researchers found that refrigerants and certain anesthetic gases have generated more than 335,000 tonnes of trifluoroacetic acid (TFA), a highly persistent "forever chemical," that has been deposited across Earth's surface since 2000. The pollutant is now showing up everywhere from rainwater to remote Arctic ice, and scientists expect levels to keep rising.
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